CRISPR/Cas9 technology has been rapidly developed. This genome editing tool shows several aspects that affect its efficiency and specificity such as Cas9 activity, target sites selection and sgRNAs design, delivery methods, off-target effects, and the incidence of homology-directed repair. In this study, the authors highlight the factors that affect the utilization of CRISPR/Cas9 as well as possible strategies to handle these problems. Addressing these issues will allow us to take better advantage of this technique.
To get content containing either thought or leadership enter:
To get content containing both thought and leadership enter:
To get content containing the expression thought leadership enter:
You can enter several keywords and you can refine them whenever you want. Our suggestion engine uses more signals but entering a few keywords here will rapidly give you great content to curate.
CRISPR/Cas9 technology has been rapidly developed. This genome editing tool shows several aspects that affect its efficiency and specificity such as Cas9 activity, target sites selection and sgRNAs design, delivery methods, off-target effects, and the incidence of homology-directed repair. In this study, the authors highlight the factors that affect the utilization of CRISPR/Cas9 as well as possible strategies to handle these problems. Addressing these issues will allow us to take better advantage of this technique.
www.geg-tech.com/Vectors